Pharmaceutical grade cellulose ether is an important excipient in the pharmaceutical industry. It is widely used in film coating, adhesive, drug film, ointment, dispersant, vegetable capsule, sustained and controlled release preparation and other pharmaceutical excipients in the pharmaceutical industry. The core technology of pharmaceutical-grade cellulose ether dedicated to pharmaceutical sustained-release preparations (including sustained-release preparations and controlled-release preparations) has been controlled by well-known foreign companies for a long time, and only a few domestic companies have mastered the production capacity of cellulose ether for controlled-release preparations, which is expensive , restricting product promotion and application and upgrading of the pharmaceutical industry. Pharmaceutical grade HPMC is an important raw material for the production of sustained and controlled release preparations. It is a pharmaceutical excipient supported by the state’s key research and development, and is in line with the development direction supported by the national industrial policy. Pharmaceutical-grade HPMC is the main raw material for the production of HPMC plant capsules, accounting for more than 90% of the raw materials of HPMC plant capsules. The prepared plant capsules have the advantages of safety and hygiene, wide applicability, no risk of cross-linking reactions, and high stability, which meet consumers’ expectations. To meet the safety and hygiene requirements of food and medicine, it is one of the important supplements and ideal substitutes for animal gelatin capsules. The demand for plant capsules in foreign markets has grown rapidly. my country started late in the field of plant capsules, with small production and sales, and great potential for future market demand. In recent years, the state has investigated and dealt with enterprises that illegally produce and use unqualified capsules, and the public’s awareness of food and drug safety has improved, which has promoted the standardized operation and industrial upgrading of the domestic gelatin industry. It is expected that plant capsules will become one of the important directions for the upgrading of the hollow capsule industry in the future, and will be the main growth point for the demand for pharmaceutical grade HPMC in the domestic market in the future. The main application fields of the company’s pharmaceutical grade cellulose ether HPMC include film coating, adhesive, drug film, ointment, dispersion, vegetable capsule, sustained-release preparation, controlled-release preparation (CR grade), etc.

In the field of medicine, capsule preparations have obvious advantages over tablets. Capsules can mask the bad smell of drugs and are easy to swallow, so they are more popular with consumers; in addition, capsules use fewer types of excipients, fewer testing items, lower research and development costs, higher research and development efficiency, and more pharmaceuticals. In the morning, the market exclusivity period of patented drugs will be longer, and the profits of new drugs for pharmaceutical companies will increase significantly accordingly. At the same time, the cost of capsules is 25%-30% lower than that of tablets. In 2007, the total global sales of capsules exceeded 310 billion capsules, of which 94% were animal capsules and 6% were plant capsules (about 18.6 billion capsules). In 2016, the global sales of plant capsules exceeded 100 billion capsules, of which the annual growth of HPMC hollow capsules The rate exceeds 25%. In my country, the market share of plant capsules still does not exceed 10%. The reason is that large-scale production of HPMC plant capsules has certain technical difficulties. Compared with developed countries, the related technologies for producing plant capsules in my country are not mature enough. There are fewer enterprises, and the output of HPMC plant capsules is relatively small, but on the other hand, as the country and the public pay more and more attention to the safety of hollow capsule products, plant capsules will become one of the important directions for the upgrading of the hollow capsule industry in the future. The main growth point of market demand for pharmaceutical grade HPMC. At present, there are still few domestic enterprises capable of producing pharmaceutical grade cellulose ethers. Representative enterprises include Shandong Head and Shandong RUITAI. Therefore, from Shandong Head’s operating data, it can be seen that the company’s subsidiaries that produce pharmaceutical-grade cellulose ethers and plant capsules contribute relatively well to the company’s profits and become a new growth point for profits.

my country’s pharmaceutical industry is in the midst of vigorous development. In 2017, enterprises above designated size in the pharmaceutical industry achieved a main business income of 2.9826 billion yuan, a year-on-year increase of 12.20%. If the pharmaceutical excipients account for 3% of the total output value of pharmaceutical preparations It is estimated that the total output value of domestic pharmaceutical excipients in 2017 was about 52.162 billion yuan. From 2009 to 2017, the compound annual growth rate of the main business income of my country’s chemical pharmaceutical preparation industry was as high as 16%, the annual compound growth rate of the main business income of the biopharmaceutical manufacturing industry was as high as 20%, and the annual compound growth rate of the main business income of the Chinese patent medicine manufacturing industry was 20%. The growth rate is as high as 16%, which shows the rapid development of my country’s pharmaceutical manufacturing industry, which will drive the rapid development of the pharmaceutical excipients industry.

In addition, Euromonitor data shows that the market size of my country’s health care products industry in 2018 was close to 160 billion yuan, a year-on-year growth rate of 9.8%. Among them, the potential application of vegetable capsules to vitamins and dietary supplements accounted for nearly 90%. It is estimated that the global production of HPMC soft capsules is close to 100 billion capsules, accounting for about 10% of the capsule market share, of which 70% come from health products, such as vitamin E soft capsules, deep-sea fish oil soft capsules, etc. The price of vegetable capsules sold by large foreign multinational groups is around 400 yuan per 10,000 capsules, corresponding to an existing market size of about 4 billion yuan. With the development of downstream industries and the increase in the penetration rate of vegetable capsules, the market size will increase accordingly.